This meeting intends to progress towards a broadly accepted framework to assess and position the safety of trace chemicals exposure from consumer products, and in particular from articles and assembled consumer goods.



Program Structure: The scientific program for this workshop is segmented according to each theme. Each presentation will be approximately 20–25 minutes long, and each theme contains a mix of invited speakers and speakers selected from submitted abstracts. Each theme will close with a moderated panel discussion that allows audience members and speakers to engage in productive dialogue to help address central questions related to each theme. Theme 5, "Towards a Risk Assessment Best Practice Framework" is intended as an interactive session that allows for rotating group dialogue among attendees.

In addition to the presentations there will also be poster sessions on Monday and Tuesday evenings. The poster sessions are intended to allow all attendees to present related research and findings, share ideas, and increase collaboration.

Detailed Scientific Program                

Monday, May 20, 2019

 

8:00 AM–8:30 AM

Attendee Breakfast

All attendees are welcome to join the meeting early for breakfast, coffee, and informal networking to start your day.

8:35 AM–9:00 AM

Opening Remarks and Welcome from the Organizing Committee and The Toxicology Forum

9:00 AM–10:40 AM

SESSION: Opening Plenary—Regulatory Landscape in the European Union and North America for Article Chemical Safety

Talks in this session set the stage for the rest of the workshop and provide perspectives from regulatory agencies and industry. Each presentation includes 5 minutes for questions.

Session Chairs:
Eddy Goelen, VITO NV
Kristin Isaacs, US EPA/NERL
Diederik Schowanek, Procter & Gamble Co., (BE)

Click Here to Download Session Speaker Abstracts:

9:00 AM–9:25 AM

Andreas Ahrens, European Chemicals Agency (ECHA): Hazardous Substances in Articles—Who Is Expected to Demonstrate Safe Use and How Can It Be Done

9:25 AM–9:50 AM

Angelika Zidek, Health Canada: Canada’s Chemicals Management Plan—The Role of Consumer Product Exposures over the Last Decade

9:50 AM–10:15 AM

Tatsiana Dudzina, ECETOC-Exposure Task Force: Low Exposures: Collaborative Research Efforts and Future Focus Areas

10:15 AM–10:40 AM

Anna Gergely, Steptoe & Johnson LLP: Lessons to Be Learned: The EU Food Contact Legislation

10:40 AM–11:00 AM

Scientific Program Break

11:00 AM – 12:20 PM

SESSION: Advances in Analytical Methods: How to Detect and Quantify Relevant Low-Level Chemical Exposure from All Routes?

Session Chairs:
Eddy Goelen, VITO NV
Pim Leonards, Vrije Universiteit Amsterdam

Each presentation includes 5-10 minutes for questions, with an additional 30 minute moderated panel discussion for speakers and audience members at the end of the session.

Click Here to Download Session Speaker Abstracts:

11:00 AM–11:20 AM

Caroline Widdowson, Markes, Inc.Advances in Sampling and Analysis of Low-Level VOC and SVOC Emissions

11:20 AM–11:40 AM

Marianne Stranger, VITO NV: The Development of Emission Test Scenarios to Assess Exposures Related to the Use of Consumer Products: The Case of the EU EPHECT Project

11:40 AM–12:00 Noon

Pim Leonards, Vrije Universiteit Amsterdam: Fast-Screening Methods for Chemicals in Consumer Products

12:00 Noon–12:20 PM

Xinrong Chen, US Consumer Product Safety Commission: US Consumer Product Safety Commission Experience in Low-Level Chemical Exposure in Consumer Products

12:20 PM–1:30 PM

Attendee Luncheon
(Included with Registration)

1:30 PM – 3:00 PM

SESSION: Advances in Analytical Methods: How to Detect and Quantify Relevant Low-Level Chemical Exposure from All Routes?

Session Chairs:
Eddy Goelen, VITO NV
Pim Leonards, Vrije Universiteit Amsterdam

1:30 PM–1:50 PM

Arno Knorr, Philip Morris International R&DCharacterization of Aerosol Exposure, Metabolism, and Pharmacokinetics for Toxicological Assessment Using In Vitro Organotypic Airway Models and Organ-on-a-Chip Liver Models 

1:50 PM–2:10 PM

Kady Krivos, Procter & GambleDetermining Relevant Low-Level Chemical Exposures for Safety Assessments of Consumer Products

2:10 PM–2:30 PM

Stuart Harrad, University of BirminghamA Protocol for Studying Human Dermal Uptake of Chemical Additives: Application to Brominated Flame Retardants in Textiles

2:30 PM–2:50 PM

Moderated Panel and Attendee Discussion on Advances in Analytical Methods

2:50 PM–3:20 PM

Scientific Program Break

3:20 PM–5:00 PM

SESSION: Experimental and/or Modeling Approaches?

Session Chairs:
John Bartzis, University of Western Macedonia 
Kristin Isaacs, US EPA/NERL

Each presentation includes 5-10 minutes for questions, with an additional 30 minute moderated panel discussion for speakers and audience members at the end of the session on Tuesday.

Click Here to Download Session Speaker Abstracts:

3:20 PM–3:40 PM

John Bartzis, University of Western MacedoniaAir Exposure Modeling from Consumer Product Use: Modeling Challenges

3:40 PM–4:00 PM

John O'Brien, Creme GlobalA Probabilistic Model of Exposure to Fragrance Materials

4:00 PM–4:20 PM

Lesa Aylward, Summit Toxicology: Exposure to Preservatives in Personal Care Products:  Case Study Comparing Biomonitoring Data to Model Predictions

4:20 PM–4:40 PM

Bas Bokkers, Netherlands National Institute for Public Health and the EnvironmentAggregate Exposure to Substances in Personal Care Products and Household Cleaning Products: The Probabilistic Aggregate Consumer Exposure Model

4:40 PM–5:00 PM

John Wambaugh, US EPA/NCCT: Fusing Exposure Data and Models to Reduce Uncertainty

5:00 PM–6:00 PM

Poster Session and Attendee Reception

Attendees will be able to enjoy posters, networking, and refreshments in a laid-back atmosphere that promotes engagement and dialogue

Click Here to Download Poster Presentation Abstracts:

 

Tuesday, May 21, 2019

 

8:00 AM–9:00 AM

Attendee Breakfast

All attendees are welcome to join the meeting early for breakfast, coffee, and informal networking to start your day.

9:00 AM–10:10 AM

SESSION: Experimental and/or Modeling Approaches?

Session Chairs:
John Bartzis, University of Western Macedonia 
Kristin Isaacs, US EPA/NERL

9:00 AM–9:20 AM

Li Li, University of Toronto Scarborough: Using Lifecycle Chemical Emission Information for Exposure- and Risk-Based Assessments

9:20 AM–9:40 AM

Jon Arnot, ARC Arnot Research and Consulting, Inc.Developing Internal Threshold of Toxicological Concern Data for Applications in Aggregate Exposure and Safety Assessments

9:40 AM–10:10 AM

Moderated Panel and Attendee Discussion on Experimental and/or Modeling Approaches

10:10 AM–12:45 PM

SESSION: Global Databases for Exposure Information

Session Chairs:
Kathie Dionisio, US EPA/NERL
Stylianos Kephalopoulos, Joint Research Centre, European Commission

Each presentation includes 5-10 minutes for questions, with an additional 30 minute moderated panel discussion for speakers and audience members at the end of the session.

Click Here to Download Session Speaker Abstracts: 

10:15 AM–10:35 AM

Peter Fantke, Technical University of DenmarkFully Quantitative, Mass-Balance-Based Framework to Consistently Quantify High-Throughput Exposure and Human Toxicity Effects for ~10,000 Chemicals Found in Consumer Product Applications

10:35 AM–10:55 AM

Scientific Program Break

10:55 AM–11:15 AM

Kathie Dionisio, US EPA/NERL: Use of Informatics Methods to Inform Rapid Chemical Exposure Assessments

11:15 AM–11:35 AM

Kristin Issacs, US EPA/NERLNew Exposure Databases from the US EPA: Harmonized Chemical, Product, and Monitoring Information

11:35 AM–11:55 AM

Ivan Rusyn, Texas A&M University: A Database for High-Throughput Exposomic Analyses of Environmental Chemicals by Solid Phase Extraction-Ion Mobility Spectrometry-Mass Spectrometry

11:55 AM–12:15 PM

Ivy Moffat, Health Canada: Exposure and Hazard Driven Prioritization for Evaluation of Chemicals in Canadian Drinking Water

12:15 PM–12:45 PM

Moderated Panel and Attendee Discussion on Global Databases for Exposure Information

12:45 PM–1:50 PM Attendee Luncheon
(Included with registration)
1:50 PM–4:50 PM

SESSION: Guidance for Practitioners, Recommendations for Policy Work and Public Communication

Session Chairs:
Silvia Campos, The Coca-Cola Company
Marusia Popovech, ExxonMobil Biomedical Sciences, Inc.

Each presentation includes 5-10 minutes for questions, with an additional 40 minute moderated panel discussion for speakers and audience members at the end of the session.

Click Here to Download Session Speaker Abstracts: 

1:50 PM–2:10 PM

Ragnar Löfstedt, King's College, LondonEvidence Based and Risk Informed Policy Making in Europe post Brexit—Possible Directions

2:10 PM–2:30 PM

Andreas Ahrens, European Chemicals Agency (ECHA): Plastic Additives Initiative—Overview of Plastic Additives in the European Market and Method for Comparison of Release Potential

2:30 PM–2:50 PM

Aurélie Haroche, Journal International de MédecineSurvey about the Perception of Substances Potentially Toxic at Low Levels in Daily Products: A Major Concern for the General Public and Health Professionals

2:50 PM–3:10 PM

Stefan Hahn, Fraunhofer-Institut für Toxikologie und Experimentelle Medizin: Framework on Exposure-Informed Adaptation of REACH Hazard Information Requirements

3:10 PM–3:40 PM

Scientific Program Break

3:40 PM–4:00 PM

Ruchir Shah, Sciome: Rapid Evidence Mapping for Health: A Case Study

4:00 PM–4:20 PM

David Zaruk, Odisee University College Brussels: Why Your Data Doesn’t Matter

4:20 PM–5:00 PM

Moderated Panel and Attendee Discussion on Guidance for Practitioners, Recommendations for Policy Work and Public Communication

7:00 PM–9:00 PM

Conference Social

Included with Registration

 

Wednesday, May 22, 2019

 

8:00 AM–9:00 AM

Attendee Breakfast

All attendees are welcome to join the meeting early for breakfast, coffee, and informal networking to start your day.

9:00 AM–12:20 PM

SESSION: Towards a Risk Assessment Best Practice Framework

Session Chairs:

Wolfgang Dekant, University of Würzburg
Diederik Schowanek, Procter & Gamble (BE)
John Wambaugh, US EPA/NCCT

The intention of this session is allow attendees to network and discuss in small groups the implications of all that has been presented at the meeting and begin discussing an informal path forward with a commitment to understanding and dialogue.

9:00 AM–9:25 AM

Session Keynote Speaker and Abstract:

Angelika Zidek, Health Canada: The Path towards a Modernized Risk Assessment Framework for Low-Level Exposures—Synthesizing Lessons Learned

9:25 AM–9:40 AM

World Cafe Method Explained {Click here for online details}

9:40 AM–11:40 AM

Roundtable Discussions

11:40 AM–12:00 Noon

Scientific Program Break and Refreshments

12:00 Noon–1:00 PM

Plenary Debrief

1:00 PM–1:15 PM

Wrap-up and Workshop Closing Remarks